Data Last Updated: Oct. 15, 2024

Percent Necrosis Post Neoadjuvant

Description

Percent Necrosis Post Neoadjuvant is a prognostic factor for bone sarcomas. For osteosarcoma and Ewing’s sarcoma/PNET, response to neoadjuvant chemotherapy is a prognostic factor. Patients with more than 90% tumor necrosis have a more favorable prognosis than those with less response. The CAP protocol for bone tumor resection provides the pathologist with specific instructions for determining the percentage of tumor necrosis. A separate method (system of Picci) may describe response to treatment in grades: grade I (macroscopic viable tumor), grade II (microscopic viable tumor), or grade III (no viable tumor). Do not code the Picci grade system in this data item.

Notes

**Note:** **Physician Statement** * Physician statement of microscopically confirmed Percent Necrosis Post Neoadjuvant Chemotherapy can be used to code this data item if no other documentation is available.
Code Description
0.0 Tumor necrosis not identified/not present
0.1-100.0 0.1 - 100.0 percent tumor necrosis
(Percentage of tumor necrosis to nearest tenth of a percent)
XXX.2 Tumor necrosis present, percent not stated
XXX.8 Not applicable: Information not collected for this case
If this item is required by your standard setter, use of code XXX.8 will result in an edit error.
XXX.9 Not documented in medical record
No histologic examined of primary site
No neoadjuvant therapy
No surgical resection of primary site is performed