Ki-67 (MIB-1)
Description
Ki-67 (MIB-1) (Proliferative Index) is a marker of cell proliferation. A high value indicates a tumor that is proliferating more rapidly. Codes and coding instructions for this data item are site-specific.Notes
**Note 1:** **Physician Statement** * Physician statement of Ki-67 (MIB-1), also referred to as the “Proliferative Index” can be used to code this data item when no other information is available. **Note 2:** **In-situ and Invasive components present** * If Ki-67 is done on both the in situ and invasive components in the primary tumor, code the Ki-67 value from the invasive component * If in situ and invasive components present and Ki-67 only done on the in-situ component in the primary tumor, code unknown **Note 3:** **Results from nodal or metastatic tissue** * Results from nodal or metastatic tissue may be used ONLY when there is no evidence of primary tumor * *Note:* In-situ is evidence of primary tumor **Note 4:** **Neoadjuvant Therapy** * Record the assay from tumor specimens prior to neoadjuvant therapy. * If neoadjuvant therapy is given and there are no Ki-67 results from pre-treatment specimens, report the findings from post-treatment specimens.| Code | Description |
|---|---|
| 0.0-100.0 | 0.0 to 100.0 percent positive: enter percent positive |
| XXX.7 | Test done, actual percentage not stated |
| XXX.8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code XXX.8 will result in an edit error.) |
| XXX.9 | Not documented in medical record Ki-67 (MIB-1) not assessed or unknown if assessed |