Multigene Signature Method
Notes
**Note 1:** Physician statement of the Multigene Signature Method can be used to code this data item. **Note 2:** Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. * Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA) * Only record tests that are based on gene assays. Don’t include other tests which use a multivariate data model to eliminate the need for genetic assays **Note 3:** Code the type of test performed. The same test should be used to record information in 3895: Multigene Signature Results. **Note 4:** Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx. * 3903: Oncotype Dx Recurrence Score-DCIS * 3904: Oncotype Dx Recurrence Score-Invasive * 3905: Oncotype Dx Risk Level-DCIS * 3906: Oncotype Dx Risk Level-Invasive| Code | Description |
|---|---|
| 1 | Mammaprint |
| 2 | PAM50 (Prosigna) |
| 3 | Breast Cancer Index |
| 4 | EndoPredict |
| 5 | Test performed, type of test unknown |
| 6 | Multiple tests, any tests in codes 1-4 |
| 7 | Test ordered, results not in chart |
| 8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.) |
| 9 | Not documented in medical record Multigene Signature Method not assessed or unknown if assessed |