Data Last Updated: May 31, 2024

Grade Post Therapy Clin (yc)

Notes

**Note 1:** Leave Grade Post Therapy Clin (yc) blank when * No neoadjuvant therapy * Clinical or pathological case only * Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor * There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological **Note 2:** Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy. **Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade. **Note 4:** Priority order for codes - Urothelial cancers (WHO/ISUP grade): use codes L, H and 9 + If only G1-G3 are documented, code 9 - Adenocarcinomas and Squamous Cell Carcinomas: use codes 1-3, 9 + If only L or H are documented, code 9 **Note 5:** G3 includes undifferentiated and anaplastic. **Note 6:** For bladder, a TURB qualifies for a clinical grade only. **Note 7:** Code 9 (unknown) when * Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented * Microscopic exam is done after neoadjuvant therapy and there is no residual cancer * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available
Code Description
1 G1: Well differentiated
2 G2: Moderately differentiated
3 G3: Poorly differentiated
L LG: Low-grade
H HG: High-grade
9 Grade cannot be assessed (GX); Unknown
<BLANK> See Note 1