Data Last Updated: Aug. 24, 2021

Grade Post Therapy Clin (yc)

Notes

**Note 1:** Leave Grade Post Therapy Clin (yc) blank when * No neoadjuvant therapy * Clinical or pathological case only * Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor * There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological **Note 2:** Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy. **Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade. **Note 4:** Codes 1-3 take priority over A-D. **Note 5:** For this grading system, the CAP Checklist refers to this as “histologic type,” instead of grade. **Note 6:** Code 9 (unknown) when * Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented * Microscopic exam is done after neoadjuvant therapy and there is no residual cancer * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available
Code Description
1 G1: Spindle cell melanoma (>90% spindle cells)
2 G2: Mixed cell melanoma (>10% epithelioid cells and <90% spindle cells)
3 G3: Epithelioid cell melanoma (>90% epithelioid cells)
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
9 Grade cannot be assessed (GX); Unknown
<BLANK> See Note 1