Microvascular Density (MVD)
Notes
**Note 1:** Physician statement of microvascular density (MVD) can be used to code this data item when no other information is available. **Note 2:** MVD is independently associated with metastatic risk. The number of immunopositive elements is labeled with a marker for vascular endothelial cells (e.g., CD34 epitope, CD31 epitope, factor VIII-related antigen) and counted from area of densest vascularization (typical field area, 0.3 mm2 squared). Higher counts are associated with shorter survival. **Note 3:** Record the results as expressed on the laboratory test. Record the information based on quartiles for laboratory standards if this is the only expression of results.| Code | Description |
|---|---|
| 00 | No vessels involved |
| 01-99 | 01-99 vessels per 0.3 square millimeter (mm2) |
| X1 | Greater than or equal to 100 vessels per 0.3 square millimeter (mm2) |
| X2 | Lowest quartile for laboratory |
| X3 | Second quartile for laboratory |
| X4 | Third quartile for laboratory |
| X5 | Highest quartile for laboratory |
| X7 | Test ordered, results not in chart |
| X8 | Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 8 may result in an edit error.) |
| X9 | Not documented in medical record Microvascular Density (MVD) not assessed or unknown if assessed |