Data Last Updated: Aug. 24, 2021

Grade Pathological - Standard non AJCC

Notes

**Note 1:** Grade Pathological must not be blank. **Note 2:** Assign the highest grade from the primary tumor. **Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade. **Note 4:** Use the grade from the **clinical work up** from the primary tumor in different scenarios based on behavior or surgical resection * **Behavior** - Tumor behavior for the clinical and the pathological diagnoses are the same AND the clinical grade is the highest grade - Tumor behavior for clinical diagnosis is invasive, and the tumor behavior for the pathological diagnosis is in situ * **Surgical Resection** - Surgical resection is done of the primary tumor and there is no grade documented from the surgical resection - Surgical resection is done of the primary tumor and there is no residual cancer * **No surgical resection** - Surgical resection of the primary tumor has not been done, but there is positive microscopic confirmation of distant metastases during the clinical time frame **Note 5:** Code 9 (unknown) when * Grade from primary site is not documented * No resection of the primary site (see exception in Note 4, Surgical resection, last bullet) * Neo-adjuvant therapy is followed by a resection (see Grade Post Therapy Path (yp)) * Grade checked "not applicable" on CAP Protocol (if available) and no other grade information is available * Clinical case only (see Grade Clinical) * There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological
Code Description
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
9 Grade cannot be assessed; Unknown