Data Last Updated: Sept. 13, 2023

Grade Clinical

This input is used for staging

Notes

**Note 1:** Grade Clinical must not be blank. **Note 2:** Assign the highest grade from the primary tumor assessed during the clinical time frame. **Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade. **Note 4:** Codes 1-5 take priority over A-E. **Note 5:** For prostate, a TURP or simple prostatectomy qualifies for a clinical grade only. **Note 6:** Code 9 (unknown) when * Grade from primary site is not documented * Clinical workup is not done (for example, cancer is an incidental finding during surgery for another condition) * Grade checked "not applicable" on CAP Protocol (if available) and no other grade information is available **Note 7:** If there is only one grade available and it cannot be determined if it is clinical or pathological, assume it is a Grade Clinical and code appropriately per Grade Clinical categories for that site, and then code unknown (9) for Grade Pathological, and blank for Grade Post Therapy Clin (yc) and Grade Post Therapy Path (yp). **Note 8:** If you are assigning an AJCC Staging System stage group * Grade is required to assign stage group * Codes A-E are treated as an unknown grade when assigning AJCC stage group * An unknown grade may result in an unknown stage group
Code Description
1 Grade Group 1: Gleason score less than or equal to 6
2 Grade Group 2: Gleason score 7
Gleason pattern 3+4
3 Grade Group 3: Gleason score 7
Gleason pattern 4+3
4 Grade Group 4: Gleason score 8
5 Grade Group 5: Gleason score 9 or 10
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
E Stated as "Gleason score 7" with no patterns documented or
Any Gleason patterns combination equal to 7 not specified in 2 or 3
9 Grade cannot be assessed; Unknown