Data Last Updated: June 9, 2025

Schema Discriminator 2: Soft Tissue Trunk and Extremities/Soft Tissue Abdomen and Thoracic

This input is used for staging

Description

The ICD-O-3 assigned topography codes for the peripheral nerve and autonomic nervous systems tumors (C47) and the connective, subcutaneous and other soft tissues (C49) primary sites are based on transverse or horizontal planes. The AJCC Staging System Soft Tissue Sarcoma of the Trunk and Extremities, and Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs base the eligible sites as either external structures or internal viscera. For example, * C493 axilla is an external site using the AJCC Staging System Soft Tissue Sarcoma of the Trunk and Extremities * C493 axillary artery is an internal site using the AJCC Staging System Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs * C475 sacrococcygeal region is a large area that may be either external or internal * Need to determine the exact area involved to assign the correct chapter * C475 external area of sacrococcygeal region uses the AJCC Staging System Soft Tissue Sarcoma of the Trunk and Extremities * C475 intrapelvic area of sacrococcygeal region uses the AJCC Staging System Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs To develop a software algorithm that can be used to send the registrar to the correct system/schema, this schema discriminator was developed. The schema discriminator is based on determining whether the structure involved is part of the external structures or the internal viscera. This is accomplished by * Terms in ICD-O-3 topography codes sorted appropriately by the physician experts when possible * Instructions on what to do when terms are not specific enough to be assigned as external structures or internal viscera * Without additional information, these may not be staged, for example C475 pelvis * With additional information, these may be determined to be external structures or internal viscera * In addition to the topography codes and terms, there is also an option of “External sites, NOS” and “Internal sites, NOS” for registrars to use to assign the schema discriminator. Registrars may need to use additional information, including physician staging, to choose the appropriate schema discriminator

Notes

**Note:** **Schema discriminator for C473, C475, C493-C495** * A schema discriminator is used to discriminate for peripheral nerve tumors (C473, C475) and connective tissue tumors (C493, C494, C495) for the subsite in which the tumor arose.
Code Description Schema ID #/Description
1 External structures (sites), NOS

***Examples*** of terms include:

Peripheral nerves and autonomic nervous system (C47)
* Pelvis (C475)
- Buttock
- Gluteal region
- Groin
- Inguinal region
- Perineum
- Sacrococcygeal region (stated as external)
* Thorax (C473)
- Axilla
- Chest wall
- Infraclavicular region
- Scapular region
- Thoracic wall

Connective, subcutaneous and other soft tissues (C49)
* Abdomen (C494)
- Abdominal wall
- Abdominal wall muscle
- Iliopsoas muscle
- Psoas muscle
- Rectus abdominis muscle
- Umbilicus
* Pelvis (C495)
- Buttock
- Gluteal region
- Gluteus maximus muscle
- Groin
- Inguinal region
- Perineum
- Sacrococcygeal region
* Thorax (C493)
- Axilla
- Chest wall
- Infraclavicular region
- Intracostal muscle
- Latissimus dorsi muscle
- Pectoralis major muscle
- Scapular region
- Thoracic wall
- Trapezius muscle
00410: Soft Tissue Trunk and Extremities
2 Internal structures and viscera (sites), NOS

***Examples*** of terms include

Peripheral nerves and autonomic nervous system (C47)
* Sacrococcygeal region (intrapelvic)

Connective, subcutaneous and other soft tissues (C49)
* Abdomen (C494)
- Abdominal aorta
- Abdominal vena cava
- Celiac artery
- Inferior vena cava
- Mesenteric artery
- Renal artery
- Vena cava
* Pelvis (C495)
- Iliac artery
- Iliac vein
* Thorax (C493)
- Aorta
- Axillary artery
- Diaphragm
- Internal mammary artery
- Subclavian artery
- Superior vena cava
- Thoracic duct
00421: Soft Tissue Abdomen and Thoracic (excluding Heart, Mediastinum, Pleura)
8 Not applicable: Case abstracted prior to 2021 update 00421: Soft Tissue Abdomen and Thoracic (excluding Heart, Mediastinum, Pleura)
9 Not specific enough to determine if external or internal

***Examples*** of terms include

Peripheral nerves and autonomic nervous system (C47)
* Pelvis (C475)
- Lumbosacral plexus
- Sacral nerve
- Sacral plexus
* Thorax (C473)
- Chest
- Intercostal nerve

Connective, subcutaneous and other soft tissues (C49)
* Thorax (C493)
- Chest, NOS
- Thorax
00459: Soft Tissue Other
<BLANK> Primary Site is not C473, C475, C493-C495, Discriminator is not necessary