Data Last Updated: June 9, 2025

NAACCR Item #3819: CEA Pretreatment Interpretation

Item # Length Source of Standard Section Name Year Implemented Version Implemented XML NAACCR ID Parent XML Element
3819 1 NAACCR Stage/Prognostic Factors 2018 18 ceaPretreatmentInterpretation Tumor
Required Status:

NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Required, site specific
CCCR Collect: Required, site specific; when available

Description
CEA (Carcinoembryonic Antigen) Pretreatment Interpretation refers to the interpretation of the CEA value prior to treatment. CEA is a glycoprotein that is produced by adenocarcinomas from all sites as well as many squamous cell carcinomas of the lung and other sites. CEA may be measured in blood, plasma or serum. CEA is a prognostic marker for adenocarcinomas of the appendix, colon and rectum and is used to monitor response to treatment
Rationale
CEA (Carcinoembryonic Antigen) is a Registry Data Collection Variable for AJCC 8. CEA (Carcinoembryonic Antigen) Pretreatment Interpretation was previously collected as Colon and Rectum, CS SSF #1.
Allowable Values
0-3, 7-9
Codes
Code Description
0 CEA negative/normal; within normal limits
1 CEA positive/elevated
2 Borderline
3 Undetermined if positive or negative (normal values not available) AND no MD interpretation
7 Test ordered, results not in chart
8 Not applicable: Information not collected for this case (If this data item is required by your standard setter, use of code 8 will result in an edit error.)
9 Not documented in medical record CEA (Carcinoembryonic Antigen) Pretreatment Interpretation not assessed or unknown if assessed
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.