Data Last Updated: June 9, 2025

NAACCR Item #3853: HER2 ISH Single Probe Copy Number

Item # Length Source of Standard Section Name Year Implemented Version Implemented XML NAACCR ID Parent XML Element
3853 4 NAACCR Stage/Prognostic Factors 2018 18 her2IshSingleProbeCopyNumber Tumor
Required Status:

NPCR Collect: No recommendation
CoC Collect: No recommendation
SEER Collect: No recommendation
CCCR Collect: No recommendation

Description
HER2 in situ hybridization (ISH) Single Probe Copy Number is the HER2 copy number based on a single probe test.
Rationale
HER2 ISH Single Probe Copy Number is a Registry Data Collection Variable in AJCC. It is a new data item for cases diagnosed 1/1/2018+.
Allowable Values
0.0-99.9, XX.1, XX.7, XX.8, XX.9
Codes
Code Description
0.0-99.9 Reported HER2 copy number of 0.0-99.9
XX.1 Reported HER2 copy number of 100 or greater
XX.7 Test ordered, results not in chart
XX.8 Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code XX.8 will result in an edit error.)
XX.9 Not documented in medical record Cannot be determined (indeterminate) Single probe test not done; only dual probe test performed HER2 ISH Single Probe Copy Number not assessed or unknown if assessed
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.