Data Last Updated: June 9, 2025

NAACCR Item #3857: High Risk Cytogenetics

Item # Length Source of Standard Section Name Year Implemented Version Implemented XML NAACCR ID Parent XML Element
3857 1 NAACCR Stage/Prognostic Factors 2018 18 highRiskCytogenetics Tumor
Required Status:

NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Required, site specific
CCCR Collect: Required, site specific; when available

Description
High Risk Cytogenetics is defined as one or more of t(4;14), t(14;16), or del 17p identified from FISH test results and is part of the staging criteria for plasma cell myeloma.
Rationale
High Risk Cytogenetics is a prognostic factor required in AJCC 8th edition, Chapter 82 *Plasma Cell Myeloma and Plasma Cell Disorders*, for staging of plasma cell myeloma.
Allowable Values
0, 1, 5, 7, 9
Codes
Code Description
0 High-risk cytogenetics not identified/not present
1 High-risk cytogenetics present
5 Schema Discriminator 1: Plasma Cell Myeloma Terminology coded to 1 or 9
7 Test ordered, results not in chart
9 Not documented in medical record High Risk Cytogenetics not assessed or unknown if assessed
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.