NAACCR Item #3863: Ki-67
Item # | Length | Source of Standard | Section Name | Year Implemented | Version Implemented | XML NAACCR ID | Parent XML Element |
---|---|---|---|---|---|---|---|
3863 | 5 | NAACCR | Stage/Prognostic Factors | 2018 | 18 | ki67 | Tumor |
Required Status:
NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Collected by SEER from CoC-accredited hospitals
CCCR Collect: No recommendation
Description
Ki-67 (MIB-1) (Proliferative Index) is a marker of cell proliferation. A high value indicates a tumor that is proliferating more rapidly. Codes and coding instructions for this data item are site-specific.
Rationale
Ki-67 (MIB-1) (Proliferative Index) is a Registry Data Collection Variable in AJCC. It was a new data item for breast cases diagnosed 1/1/2018+. It will apply to neuroendocrine tumors (NET) of the gastrointestinal tract (AJCC Chapters 29 – 34) for cases diagnosed 1/1/2021+. High Ki-67 is an adverse prognostic factor and Ki-67 is a component of grade for these tumors. NCCN guidelines recommend that tumor differentiation, mitotic rate and Ki-67 should be recorded in the pathology report for these tumors.
Allowable Values
0.0-100.0, XXX.4, XXX.5, XXX.6, XXX.7, XXX.8, XXX.9
Codes
Code | Description |
---|---|
0.0-100.0 | 0.0 to 100.0 percent positive: enter percent positive |
XXX.4 | Ki-67 stated as less than 3% |
XXX.5 | Ki-67 stated as 3%-20% |
XXX.6 | Ki-67 stated as greater than 20% |
XXX.7 | Test done, actual percentage not stated |
XXX.8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code XXX.8 will result in an edit error.) |
XXX.9 | Not documented in medical record Ki-67 (MIB-1) not assessed or unknown if assessed |
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.