Data Last Updated: June 9, 2025

NAACCR Item #3865: KIT Gene Immunohistochemistry

Item # Length Source of Standard Section Name Year Implemented Version Implemented XML NAACCR ID Parent XML Element
3865 1 NAACCR Stage/Prognostic Factors 2018 18 kitGeneImmunohistochemistry Tumor
Required Status:

NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Collected by SEER from CoC-accredited hospitals
CCCR Collect: Required, site specific; when available

Description
KIT Gene Immunohistochemistry (IHC) is the expression of the KIT gene in tumor tissue specimens based on immunohistochemical (IHC) stains. A positive test is a diagnostic and predictive marker for GIST tumors.
Rationale
KIT Gene Immunohistochemistry (IHC) is a Registry Data Collection Variable in AJCC. This data item was previously collected for GIST schemas in CS (different SSF’s).
Allowable Values
0, 1, 7-9
Codes
Code Description
0 KIT negative/normal; within normal limits
1 KIT positive
7 Test ordered, results not in chart
8 Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 8 may result in an edit error.)
9 Not documented in medical record Cannot be determined by pathologist KIT not assessed or unknown if assessed
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.