NAACCR Item #3894: Multigene Signature Method
| Item # | Length | Source of Standard | Section Name | Year Implemented | Version Implemented | XML NAACCR ID | Parent XML Element |
|---|---|---|---|---|---|---|---|
| 3894 | 1 | NAACCR | Stage/Prognostic Factors | None | None | multigeneSignatureMethod | Tumor |
Required Status:
NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Required, site specific
CCCR Collect: No recommendation
Description
Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. This data item identifies the multigene signature method used. Oncotype Dx is coded elsewhere.
Rationale
Multigene Signature Method is a Registry Data Collection Variable in AJCC. It was previously collected as Breast, CS SSF #22. See also Multigene Signature Results.
Allowable Values
1-9
Codes
| Code | Description |
|---|---|
| 1 | Mammaprint |
| 2 | PAM50 (Prosigna) |
| 3 | Breast Cancer Index |
| 4 | EndoPredict |
| 5 | Test performed, type of test unknown |
| 6 | Multiple tests, any tests in codes 1-4 |
| 7 | Test ordered, results not in chart |
| 8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.) |
| 9 | Not documented in medical record Multigene Signature Method not assessed or unknown if assessed |
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.