NAACCR Item #3895: Multigene Signature Results
| Item # | Length | Source of Standard | Section Name | Year Implemented | Version Implemented | XML NAACCR ID | Parent XML Element |
|---|---|---|---|---|---|---|---|
| 3895 | 2 | NAACCR | Stage/Prognostic Factors | 2018 | 18 | multigeneSignatureResults | Tumor |
Required Status:
NPCR Collect: No recommendation
CoC Collect: Required, site specific
SEER Collect: Required, site specific
CCCR Collect: No recommendation
Description
Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. This data item identified the multigene signature result. Oncotype Dx is coded elsewhere.
Rationale
Multigene Signature Results is a Registry Data Collection Variable in AJCC. It was previously collected as Breast, CS SSF #23. See also Multigene Signature Method.
Allowable Values
00-99, X1, X2, X3, X4, X7, X8, X9
Codes
| Code | Description |
|---|---|
| 00-99 | Enter actual recurrence score *Note*: Depending on the test, the range of values may be different |
| X1 | Score 100 |
| X2 | Low risk |
| X3 | Moderate [intermediate] risk |
| X4 | High risk |
| X7 | Test ordered, results not in chart |
| X8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code X8 will result in an edit error.) |
| X9 | Not documented in medical record Multigene Signature Results not assessed or unknown if assessed |
Code Notes
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.