Version 25
Data Item #3852: HER2 ISH Dual Probe Ratio

Length: 4
Source of Standard: NAACCR
Section Name: Stage/Prognostic Factors
Year Implemented: 2018
Version Implemented: 18
Record Types: A, M, C, I

XML NAACCR ID: her2IshDualProbeRatio

Parent XML Element: Tumor

Required Status:

NPCR Collect: . - No recommendations
CoC Collect: . - No recommendations
SEER Collect: . - No recommendations
CCCR Collect: . - No recommendations

Description:

HER2 in situ hybridization (ISH) Dual Probe Ratio is the summary score for HER2 testing using a dual probe. The test will report results for both HER2 and CEP17, the latter used as a control. The HER2/CEP17 ratio is reported.

Rationale:

HER2 ISH Dual Probe Ratio is a Registry Data Collection Variable in AJCC. It is a new data item for cases diagnosed 1/1/2018+.

Item Data Type:

text

Allowable Values

0.0-99.9, XX.2, XX.3, XX.7, XX.8, XX.9

Codes:

0.0-99.9	Ratio of 0.0 to 99.9
XX.2	Less than 2.0
XX.3	Greater than or equal to 2.0
XX.7	Test ordered, results not in chart
XX.8	Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code XX.8 will result in an edit error.)
XX.9	Not documented in medical record Results cannot be determined (indeterminate) Dual probe test not done; only single probe test performed HER2 ISH Dual Probe Ratio not assessed or unknown if assessed

Code Notes:

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.

Version 25 Data Item #3852: HER2 ISH Dual Probe Ratio