* indicates required field
Length: 5
Source of Standard: NAACCR
Section Name: Stage/Prognostic Factors
Year Implemented: 2018
Version Implemented: 18
Record Types: A, M, C, I
XML NAACCR ID: ki67
Parent XML Element: Tumor
Required Status:
NPCR Collect: . - No recommendations
CoC Collect: RS - Required, site specific
SEER Collect: RC - Collected by SEER from CoC-accredited hospitals
CCCR Collect: . - No recommendations
Description:
Ki-67 (MIB-1) (Proliferative Index) is a marker of cell proliferation. A high value indicates a tumor that is proliferating more rapidly. Codes and coding instructions for this data item are site-specific.
Rationale:
Ki-67 (MIB-1) (Proliferative Index) is a Registry Data Collection Variable in AJCC. It was a new data item for breast cases diagnosed 1/1/2018+. It will apply to neuroendocrine tumors (NET) of the gastrointestinal tract (AJCC Chapters 29 – 34) for cases diagnosed 1/1/2021+. High Ki-67 is an adverse prognostic factor and Ki-67 is a component of grade for these tumors. NCCN guidelines recommend that tumor differentiation, mitotic rate and Ki-67 should be recorded in the pathology report for these tumors.
Item Data Type:
text
Allowable Values
0.0-100.0, XXX.4, XXX.5, XXX.6, XXX.7, XXX.8, XXX.9
Codes:
0.0-100.0 |
0.0 to 100.0 percent positive: enter percent positive |
|---|---|
XXX.4 |
Ki-67 stated as less than 3% |
XXX.5 |
Ki-67 stated as 3%-20% |
XXX.6 |
Ki-67 stated as greater than 20% |
XXX.7 |
Test done, actual percentage not stated |
XXX.8 |
Not applicable: Information not collected for this case |
XXX.9 |
Not documented in medical record |
Code Notes:
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.