CiNA Explorer - NAACCR Cancer Statistics
Cancer Site Definitions
The cancer sites available in CiNA*Explorer are primarily defined using the SEER Site Recode ICD-O-3/WHO 2008 variable. However, there are additional sites included that are defined below and are based on specific behaviors and/or histologies, and only valid for specific years.
Combined Cancer Site Groupings
HPV Associated Sites
The following cancer site definitions are used to define the HPV Associated Sites group based on the HPV Associated Sites as defined by CDC.
All cancer diagnoses for this group are microscopically confirmed.
- Primary site code(s): C210-C212, C218
- ICD-O-3 histology codes: 8050-8084 and 8120-8131
- Primary site code(s): C53.0-53.9
- ICD-O-3 histology codes: 8010-8671 and 8940-8941
- Primary site code(s): C001.9, C002.4, C002.8, C005.1, C005.2, C009.0, C009.1, C009.8-C009.9, C010.0-C010.4, C010.8-C010.9, C014.0, C014.2, C014.8
- ICD-O-3 histology codes: 8050-8086 and 8120-8131
- Primary site code(s): C60.0-C60.9
- ICD-O-3 histology codes: 8050-8084 and 8120-8131
- Primary site code(s): C52.9
- ICD-O-3 histology codes: 8050-8084 and 8120-8131
- Primary site code(s): C51.0-C51.9
- ICD-O-3 histology codes: 8050-8084 and 8120-8131
Tobacco Associated Sites1
The following cancer site definitions are used to define the Tobacco Associated Sites group.
The cancer sites included, with the exception of Acute Myeloid Leukemia, are restricted to histology codes 8000-9049, 9056-9139, and 9141-9589 (excluding mesothelioma, Kaposi sarcoma, and hematopoietic cancers)
- ICD-O-3 histology codes: 9840, 9861, 9865-9867, 9869, 9871-9874, 9895-9898, 9910-9911, and 9920
- Primary site code(s): C53.0-53.9
- Primary site code(s): C18.0-20.9 and C26.0
- Primary site code(s): C15.0-C15.9
- Primary site code(s): C64.9-65.9
- Primary site code(s): C32.0-32.9
- Primary site code(s): C22.0
- Primary site code(s): C00.0-C14.8
- Primary site code(s): C25.0-25.9
- Primary site code(s): C16.0-16.9
- Primary site code(s): C33.9-34.9
- Primary site code(s): C67.0-67.9
1 US Department of Health and Human Services. The health consequences of smoking-50 years of progress: a report of the Surgeon General. Atlanta, GA: US Department of Health and Human Services, CDC; 2014.
Screenable Cancers
The following cancer site definitions are used to define the Screenable Cancers group.
The cancer sites in this group are defined using the SEER Site Recode ICD-O-3/WHO 2008 variable.
Obesity Associated Sites
The following cancer site definitions are used to define the Obesity Associated Sites group based on the Obesity and Cancer risk factor guidelines by CDC.
- Primary site code(s): C15.0–C15.9
- ICD-O-3 histology codes: 8140–8575
- Additional restrictions: Microscopically confirmed cases
- Primary site code(s): C16.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C18.0–C20.9, C26.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C22.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C23.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C25.0–C25.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C42.1
- ICD-O-3 histology codes: 9732
- Primary site code(s): C50.0–C50.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Additional restrictions: Female cases only and age at diagnosis ≥ 50
- Primary site code(s): C54.0–C54.9, C55.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C56.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C64.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C70.0-C70.1, 70.9
- ICD-O-3 histology codes: 9530-9539
- Primary site code(s): C73.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
Alcohol Associated Sites
The following cancer site definitions are used to define the Alcohol Associated Sites group based on the Alcohol and Cancer risk factor guidelines by CDC.
- Primary site code(s): C00.0–C14.8
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C15.0-15.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C18.0–C20.9, C26.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C22.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C32.0–C32.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C50.0–C50.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Additional restrictions: Female cases only
Physical Inactivity Associated Sites
The following cancer site definitions are used to define the Physical Inactivity Associated Sites group based on the Physical Activity and Cancer risk factor guidelines by CDC.
- Primary site code(s): C18.0–C18.9, C26.0
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Primary site code(s): C50.0–C50.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
- Additional restrictions: Female cases only and age at diagnosis ≥ 50
- Primary site code(s): C54.0–C54.9, C55.9
- ICD-O-3 histology codes: 8000–9049, 9056–9139, 9141–9589
Special Cancer Site Definitions
Brain and ONS (Benign/Borderline)- Only valid for years of diagnosis 2004+
- Site recode ICD-O-3/WHO 2008 = Brain and Other Nervous System
- Behavior = Benign or Borderline malignancy